Protirelin
CAS No. 24305-27-9
Protirelin ( Synthetic thyrotropin-releasing factor | TRF )
产品货号. M18294 CAS No. 24305-27-9
Protirelin 是一种三肽,可刺激促甲状腺素和催乳素的释放。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥381 | 有现货 |
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10MG | ¥527 | 有现货 |
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25MG | ¥1094 | 有现货 |
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50MG | ¥1758 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Protirelin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Protirelin 是一种三肽,可刺激促甲状腺素和催乳素的释放。
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产品描述Protirelin is a tripeptide that stimulates the release of thyrotropin and prolactin.
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体外实验——
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体内实验Protirelin (TRH) is an evolutionarily ancient neuropeptide, having its origin before the divergence of protostomes and deuterostomes, and may ancestrally have been involved in the control of postembryonic growth and reproduction. The effect of the thyrotropin-releasing hormone (Protirelin, TRH), one of the hypothalamic releasing hormones, on body temperature is investigated in the rat. Protirelin, in doses of 1, 5, 10 and 20 mg/kg, is injected intraperitoneally to male Wistar rats weighing 200-250 g. Protirelin causes a temporary rise in body temperature dose-dependently. The thyroidectomized rats injected 20 mg/kg of Protirelin which induces a significant hyperthermia in the sham-operated animals, fail to show a rise in body temperature. The present results suggest that a release of thyroid hormone might participate in the hyperthermic action of Protirelin.
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同义词Synthetic thyrotropin-releasing factor | TRF
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通路Others
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靶点Other Targets
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受体Thyroid hormone receptor
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研究领域Others-Field
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适应症——
化学信息
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CAS Number24305-27-9
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分子量362.38
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分子式C16H22N6O4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 250 mg/mL (689.88 mM)
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SMILESO=C(N)[C@@H]3CCCN3C(=O)[C@H](Cc1cncn1)NC(=O)[C@@H]2CCC(=O)N2
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Van Sinay E,etal.Evolutionarily conserved TRH neuropeptide pathway regulates growth in Caenorhabditis elegans.Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4065-E4074.
产品手册
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