Pomalidomide-PEG2-CO2H
CAS No. 2140807-17-4
Pomalidomide-PEG2-CO2H ( Pomalidomide-PEG2-C2-acid; Pomalidomide 4'-PEG2-acid )
产品货号. M28267 CAS No. 2140807-17-4
Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥486 | 有现货 |
|
10MG | ¥713 | 有现货 |
|
25MG | ¥1191 | 有现货 |
|
50MG | ¥2130 | 有现货 |
|
100MG | ¥3119 | 有现货 |
|
200MG | ¥4666 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Pomalidomide-PEG2-CO2H
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.
-
产品描述Pomalidomide-PEG2-CO2H is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a 2-unit PEG linker.(In Vitro):PROTACs contain two distinct ligands, one for the E3 ubiquitin ligase and the other for the target protein, linked by a linker.
-
同义词Pomalidomide-PEG2-C2-acid; Pomalidomide 4'-PEG2-acid
-
通路Others
-
靶点Other Targets
-
受体EGFR
-
研究领域——
-
适应症——
化学信息
-
CAS Number2140807-17-4
-
分子量433.4
-
分子式C20H23N3O8
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESO=C(O)CCOCCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Fry DW, et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):12022-7.
产品手册
关联产品
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
-
Annaosanchun
Annaosanchun(YC-6) is potentially for the treatment of acute ischemic stroke (AIS).
-
AP20187
AP20187 (B/B Homodimerizer) is a cell-permeable ligand used to dimerize FK506-binding protein (FKBP) fusion proteins. And it initiate biological signaling cascades and gene expression or disrupt protein-protein interactions.