021-51111890
购物车（）
sales@molnova.cn
Poloxin
CAS No. 321688-88-4
Poloxin ( —— )
产品货号. M24255 CAS No. 321688-88-4
Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ￥389 | 有现货 |
|
| 25MG | ￥932 | 有现货 |
|
| 50MG | ￥1669 | 有现货 |
|
| 100MG | ￥2479 | 有现货 |
|
| 200MG | ￥3694 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Poloxin
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).
-
产品描述Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).
-
同义词——
-
通路Cell Cycle/DNA Damage
-
靶点PLK
-
受体PLK1;PLK2;PLK3
-
研究领域——
-
适应症——
化学信息
-
CAS Number321688-88-4
-
分子量297.4
-
分子式C18H19NO3
-
纯度>98% (HPLC)
-
溶解度DMSO:14 mg/mL (43.72 mM; Need ultrasonic)
-
SMILESCC(C)C(C(C=C1C)=O)=C/C1=N/OC(c1c(C)cccc1)=O
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Yuan J, et al. Polo-box domain inhibitor poloxin activates the spindle assembly checkpoint and inhibits tumor growth in vivo. Am J Pathol. 2011 Oct;179(4):2091-9.
产品手册
关联产品
-
3MB-PP1
3MB-PP1 is an inhibitor of Polo-like kinase 1 (PLK1) and inhibits Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK) with an IC50 of 2 μM.
-
Tebanicline
Tebanicline (ABT-594, Ebanicline) acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.
-
Poloxin
Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).
