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Polaprezinc

CAS No. 107667-60-7

Polaprezinc ( Polaprezinc; Z 103 )

产品货号. M17799 CAS No. 107667-60-7

Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-ulcer, anti-oxidant and anti-inflammatory activities.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
10MG ¥340 有现货
25MG ¥543 有现货
50MG ¥786 有现货
100MG ¥1199 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Polaprezinc
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-ulcer, anti-oxidant and anti-inflammatory activities.
  • 产品描述
    Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities. Upon administration, polaprezinc increases the expression of various anti-oxidant enzymes, such as superoxide dismutase 1 (SOD-1), SOD-2, heme oxygenase-1 (HO-1), glutathione S-transferase (GST), glutathione peroxidase (GSH-px), peroxidredoxin-1 (PRDX1; PRXI) and PRXD5 (PRXV) in the gastric mucosa, which protect cells against reactive oxygen species (ROS).
  • 同义词
    Polaprezinc; Z 103
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    107667-60-7
  • 分子量
    289.63
  • 分子式
    C9H12N4O3Zn
  • 纯度
    98%
  • 溶解度
    H2O : 3.37 mg/mL 11.68 mM; DMSO : < 1 mg/mL
  • SMILES
    NCCC(=O)N1[Zn]OC(=O)[C@@H]1Cc1cnc[nH]1
  • 化学全称
    catena-Poly(zinc-mu-(beta-alanyl-L-histidinato(2(-))-N,N(sup N),O:N(sup tau)))

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Odawara S, et al. Polaprezinc protects normal intestinal epithelium against exposure to ionizing radiation in mice. Mol Clin Oncol. 2016 Oct;5(4):377-381.
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