Picrocrocin ( —— )

产品货号. M21787 CAS No. 138-55-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Picrocrocin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Picrocrocin，一种在 Cochliobolus sativus 花中发现的类胡萝卜素。
产品描述

Picrocrocin, an apocarotenoid found in the flowers of Cochliobolus sativus. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells.
体外实验

Picrocrocin exerted growth inhibitory effects on the SK-MEL-2 melanoma cells. The IC50 of picrocrocin against the SK-MEL-2 cells was 20 μM at 24-h incubation. The antiproliferative activity of picrocrocin was due to apoptosis and cell cycle arrest. In addition, picrocrocin enhanced the ROS levels and decreased the MMP levels of SK-MEL-2 cells. Finally, picrocrocin inhibited the JAK/STAT5 signalling pathway in the SK-MEL-2 melanoma cells.
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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CAS Number

138-55-6
分子量

330.37
分子式

C??H??O?
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 100 mg/mL (302.69 mM)
SMILES

OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@@]1([H])O[C@H]2CC(C)(C(C=O)=C(C)C2)C
化学全称

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计算器

产品手册

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