Picolinamide ( —— )

产品货号. M18028 CAS No. 1452-77-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Picolinamide
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Picolinamide 被发现是大鼠胰岛细胞核聚 (ADP-核糖) 合成酶的强抑制剂。
产品描述

Picolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
体外实验

Picolinamide (10 μM-1 mM) inhibits Poly(ADP-ribose) synthetase activity.Picolinamide (2 mM) protects against streptozotocin-induced depression of proinsulin synthesis in isolated pancreatic islets of rats.
体内实验

Picolinamide (4 mmol/kg, i.p., rats) inhibits Na+/phosphate cotransport by isolated renal brush border membrane vesicles.Picolinamide (250 mg/kg, i.p., rats) enhances the tumorigenic effect of Streptozotocin and Alloxan on islet B-cells. Animal Model:Rats Dosage:4 mmol/kg Administration:Intraperitoneal injection (i.p.)Result:Increased renal cortical NAD content (1.5 fold).
同义词

——
通路

Others
靶点

Other Targets
受体

PARP
研究领域

Cancer
适应症

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计算器

产品手册

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