
Picolinamide
CAS No. 1452-77-3
Picolinamide ( —— )
产品货号. M18028 CAS No. 1452-77-3
Picolinamide 被发现是大鼠胰岛细胞核聚 (ADP-核糖) 合成酶的强抑制剂。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
25MG | ¥243 | 有现货 |
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50MG | ¥340 | 有现货 |
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100MG | ¥470 | 有现货 |
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200MG | ¥778 | 有现货 |
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500MG | ¥1466 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Picolinamide
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Picolinamide 被发现是大鼠胰岛细胞核聚 (ADP-核糖) 合成酶的强抑制剂。
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产品描述Picolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
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体外实验Picolinamide (10 μM-1 mM) inhibits Poly(ADP-ribose) synthetase activity.Picolinamide (2 mM) protects against streptozotocin-induced depression of proinsulin synthesis in isolated pancreatic islets of rats.
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体内实验Picolinamide (4 mmol/kg, i.p., rats) inhibits Na+/phosphate cotransport by isolated renal brush border membrane vesicles.Picolinamide (250 mg/kg, i.p., rats) enhances the tumorigenic effect of Streptozotocin and Alloxan on islet B-cells. Animal Model:Rats Dosage:4 mmol/kg Administration:Intraperitoneal injection (i.p.)Result:Increased renal cortical NAD content (1.5 fold).
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同义词——
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通路Others
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靶点Other Targets
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受体PARP
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研究领域Cancer
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适应症——
化学信息
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CAS Number1452-77-3
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分子量122.12
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分子式C6H6N2O
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纯度>98% (HPLC)
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溶解度In Vitro:?H2O : 100 mg/mL (818.87 mM)
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SMILESC1=CC=NC(=C1)C(=O)N
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册




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