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PTP1B-IN-4
CAS No. 765317-72-4
PTP1B-IN-4 ( FRJ; NUN17724; NUN-17724; NUN 17724; PTP1B inhibitor 4; PTP1B-inhibitor-4; )
产品货号. M27767 CAS No. 765317-72-4
PTP1B-IN-4 is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥8068 | 有现货 |
|
| 100MG | ￥14094 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PTP1B-IN-4
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述PTP1B-IN-4 is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes.
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产品描述PTP1B-IN-4 is an allosteric PTP1B inhibitor with an IC50 of 8 μM. PTP1B-IN-4 can be used in studies about obesity and diabetes.(In Vitro):In CHO cells overexpressing human IR, PTP1B-IN-4 (250 μM) stimulates the phosphorylation of insulin receptors. PTP1B-IN-4 induces phosphorylation of IRS-1 and Akt which are proteins downstream of the insulin receptor.
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同义词FRJ; NUN17724; NUN-17724; NUN 17724; PTP1B inhibitor 4; PTP1B-inhibitor-4;
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通路Metabolic Enzyme/Protease
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靶点Phosphatase
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受体FAK
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研究领域——
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适应症——
化学信息
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CAS Number765317-72-4
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分子量741.5
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分子式C26H19Br2N3O7S3
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纯度>98% (HPLC)
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溶解度——
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SMILESCCc1oc2cc(ccc2c1C(=O)c1cc(Br)c(O)c(Br)c1)S(O)(=O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Yang XH, Xiang L, Li X, Zhao TT, Zhang H, Zhou WP, Wang XM, Gong HB, Zhu HL. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20(9):2789-95.
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