021-51111890
购物车（）
sales@molnova.cn
PSB-603
CAS No. 1092351-10-4
PSB-603 ( PSB 603 )
产品货号. M27690 CAS No. 1092351-10-4
Adenosine A2B receptor antagonist.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥3224 | 有现货 |
|
| 10MG | ￥4795 | 有现货 |
|
| 25MG | ￥7671 | 有现货 |
|
| 50MG | ￥10368 | 有现货 |
|
| 100MG | ￥14013 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称PSB-603
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Adenosine A2B receptor antagonist.
-
产品描述Adenosine A2B receptor antagonist.(In Vitro):In peripheral T cells, PSB-603 (100 nM) inhibits NECA-stimulated IL-6 release about 3-fold. PSB-603 (10 μM) shows no affinity for the human and rat A1 and A2A and human A3 receptors.(In Vivo):PSB-603 (5 mg/kg; i.p.) significantly reduces inflammation in local and systemic mice models of inflammation. In the inflamed paw, PSB-603 significantly decreases the levels of the inflammatory cytokines including IL-6, TNF-α and of ROS. PSB-603 reduces inflammation of the peritoneum by decreasing the infiltration of leukocytes.
-
同义词PSB 603
-
通路Others
-
靶点Other Targets
-
受体——
-
研究领域——
-
适应症——
化学信息
-
CAS Number1092351-10-4
-
分子量529.0
-
分子式C24H25ClN6O4S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCCCn1c(O)nc2nc([nH]c2c1=O)-c1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1ccc(Cl)cc1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Edward Scolnick, et al. Uses of paralog-selective inhibitors of gsk3 kinases. US20160375006A1.
产品手册
关联产品
-
Z-VRPR-FMK trifluoro...
Irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.
-
Isovitexin 2-O-arabi...
Isovitexin 2''-O-arabinoside is a flavonoid found in the alfalfa plant.
-
Isokaempferide
Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by reducing neutrophil degranulation, myeloperoxidase activity, mediators as well as TNF-alpha secretion.
