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PSB-603

CAS No. 1092351-10-4

PSB-603 ( PSB 603 )

产品货号. M27690 CAS No. 1092351-10-4

Adenosine A2B receptor antagonist.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥3224 有现货
10MG ¥4795 有现货
25MG ¥7671 有现货
50MG ¥10368 有现货
100MG ¥14013 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    PSB-603
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Adenosine A2B receptor antagonist.
  • 产品描述
    Adenosine A2B receptor antagonist.(In Vitro):In peripheral T cells, PSB-603 (100 nM) inhibits NECA-stimulated IL-6 release about 3-fold. PSB-603 (10 μM) shows no affinity for the human and rat A1 and A2A and human A3 receptors.(In Vivo):PSB-603 (5 mg/kg; i.p.) significantly reduces inflammation in local and systemic mice models of inflammation. In the inflamed paw, PSB-603 significantly decreases the levels of the inflammatory cytokines including IL-6, TNF-α and of ROS. PSB-603 reduces inflammation of the peritoneum by decreasing the infiltration of leukocytes.
  • 同义词
    PSB 603
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1092351-10-4
  • 分子量
    529.0
  • 分子式
    C24H25ClN6O4S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CCCn1c(O)nc2nc([nH]c2c1=O)-c1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1ccc(Cl)cc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Edward Scolnick, et al. Uses of paralog-selective inhibitors of gsk3 kinases. US20160375006A1.
产品手册
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