PRMT6-IN-3

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

PRMT6-IN-3 (compound 25) 是一种选择性的 PRMT6 抑制剂，IC50 值为 192 nM。PRMT6-IN-3 可以诱导癌细胞凋亡 (apoptosis)，具有抗癌活性。

PRMT6-IN-3 (compound 25) is a selective PRMT6 inhibitor with an IC50 value of 192 nM. PRMT6-IN-3 can induce apoptosis in cancer cells and has anticancer activity.

PRMT6-IN-3(compound 25) (80 μM, 3-7 days) has anti-proliferative activity against HCC827 and MDA-MB-435 cells. PRMT6-IN-3(compound 25) (0-40 μM, 72 h) significantly induces apoptosis of cancer cells in a dose-dependent manner. Among them, a concentration of 40 μM could induce apoptosis in 43.44% and 35.08% of HCC827 and MDA-MB-435 cells, respectively.

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Others

Other Targets

Histone Methyltransferase | Apoptosis

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2890765-10-1

374.5

C19H26N4O2S

>98% (HPLC)

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C(N(CCNC)C)C1=CC(=CN=C1)C2=CC=C(NS(=O)(=O)C3CC3)C=C2

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(-20℃)

With Ice Pack

≥ 2 years