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PMEDAP
CAS No. 113852-41-8
PMEDAP ( —— )
产品货号. M28188 CAS No. 113852-41-8
PMEDAP 是莫洛尼鼠肉瘤病毒 (MSV) 诱导的肿瘤形成和相关死亡率的有效抑制剂，也是人类免疫缺陷病毒 (HIV) 复制的抑制剂。 PMEDAP 还具有抗鼠巨细胞病毒 (MCMV) 活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥640 | 有现货 |
|
| 5MG | ￥988 | 有现货 |
|
| 10MG | ￥1596 | 有现货 |
|
| 25MG | ￥3686 | 有现货 |
|
| 50MG | ￥5443 | 有现货 |
|
| 100MG | ￥7744 | 有现货 |
|
| 500MG | ￥15552 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PMEDAP
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述PMEDAP 是莫洛尼鼠肉瘤病毒 (MSV) 诱导的肿瘤形成和相关死亡率的有效抑制剂，也是人类免疫缺陷病毒 (HIV) 复制的抑制剂。 PMEDAP 还具有抗鼠巨细胞病毒 (MCMV) 活性。
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产品描述PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP also has anti-murine cytomegalovirus (MCMV) activity.(In Vivo):In Three-week-old male NMRI mice inoculated with MSV, PMEDAP (0.25-5 mg/kg; IP; daily;) effected a significant delay in tumor appearance and an enhancement of the survival rate of tumor-bearing mice. PMEDAP also suppressed tumor formation and mortality in a dose-dependent manner.
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体外实验——
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体内实验PMEDAP (0.25-5 mg/kg; IP; daily; starting on the day of MSV-infected and continuing for an additional four days) causes a dose-dependent suppression of tumor formation and mortality in newborn mice inoculated with MSV. Animal Model:Three-week-old male NMRI mice Dosage:0.25 mg/kg, 1 mg/kg, 5 mg/kg Administration:IP; daily; starting on the day of infection and continuing for an additional four days Result:Effected a significant delay in tumor appearance and an enhancement of the survival rate of tumor-bearing mice.
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number113852-41-8
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分子量288.2
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分子式C8H13N6O4P
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纯度>98% (HPLC)
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溶解度In Vitro:?0.1 M NaOH : 14.29 mg/mL (49.)
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SMILESNc1c2ncn(CCOCP(O)(O)=O)c2nc(N)n1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Strupp C, Quesnot N, Richert L, Moore J, Bomann WH, Singh P. Weight of evidence and human relevance evaluation of the benfluralin mode of action in rodents (Part I): Liver carcinogenesis. Regul Toxicol Pharmacol. 2020 Nov;117:104758.
产品手册
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