• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

PMEDAP

CAS No. 113852-41-8

PMEDAP ( —— )

产品货号. M28188 CAS No. 113852-41-8

PMEDAP 是莫洛尼鼠肉瘤病毒 (MSV) 诱导的肿瘤形成和相关死亡率的有效抑制剂,也是人类免疫缺陷病毒 (HIV) 复制的抑制剂。 PMEDAP 还具有抗鼠巨细胞病毒 (MCMV) 活性。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥640 有现货
5MG ¥988 有现货
10MG ¥1596 有现货
25MG ¥3686 有现货
50MG ¥5443 有现货
100MG ¥7744 有现货
500MG ¥15552 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    PMEDAP
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    PMEDAP 是莫洛尼鼠肉瘤病毒 (MSV) 诱导的肿瘤形成和相关死亡率的有效抑制剂,也是人类免疫缺陷病毒 (HIV) 复制的抑制剂。 PMEDAP 还具有抗鼠巨细胞病毒 (MCMV) 活性。
  • 产品描述
    PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP also has anti-murine cytomegalovirus (MCMV) activity.(In Vivo):In Three-week-old male NMRI mice inoculated with MSV, PMEDAP (0.25-5 mg/kg; IP; daily;) effected a significant delay in tumor appearance and an enhancement of the survival rate of tumor-bearing mice. PMEDAP also suppressed tumor formation and mortality in a dose-dependent manner.
  • 体外实验
    ——
  • 体内实验
    PMEDAP (0.25-5 mg/kg; IP; daily; starting on the day of MSV-infected and continuing for an additional four days) causes a dose-dependent suppression of tumor formation and mortality in newborn mice inoculated with MSV. Animal Model:Three-week-old male NMRI mice Dosage:0.25 mg/kg, 1 mg/kg, 5 mg/kg Administration:IP; daily; starting on the day of infection and continuing for an additional four days Result:Effected a significant delay in tumor appearance and an enhancement of the survival rate of tumor-bearing mice.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    113852-41-8
  • 分子量
    288.2
  • 分子式
    C8H13N6O4P
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?0.1 M NaOH : 14.29 mg/mL (49.)
  • SMILES
    Nc1c2ncn(CCOCP(O)(O)=O)c2nc(N)n1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Strupp C, Quesnot N, Richert L, Moore J, Bomann WH, Singh P. Weight of evidence and human relevance evaluation of the benfluralin mode of action in rodents (Part I): Liver carcinogenesis. Regul Toxicol Pharmacol. 2020 Nov;117:104758.
产品手册
关联产品
  • p-Hydroxyphenethyl a...

    p-Hydroxyphenethyl anisate, a natural product from Notopterygium forbe-siiBoiss, is a novel polymeric sustained-release material that, after block copolymerization with AAPBA, produces nanoparticles with good pH sensitivity, glucose sensitivity, insulin loading rate, and stability.

  • Exoticin

    Exoticin shows antinociceptive and neuropharmacological activities, it could be considered as a suitable candidate for the development of analgesic and anxiolytic agents.

  • 3-Oxopomolic acid

    Pomonic acid is a triterpenoid that significantly inhibits cholesterol ester accumulation and suppresses the acyl coenzyme A:cholesterol acyltransferase ( ACAT ) activity.