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PKR-IN-C16
CAS No. 608512-97-6
PKR-IN-C16 ( —— )
产品货号. M22715 CAS No. 608512-97-6
PKR-IN-C16 is a specific protein kinase (PKR) inhibitor.?PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM.?
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥413 | 有现货 |
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| 5MG | ￥648 | 有现货 |
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| 10MG | ￥1126 | 有现货 |
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| 25MG | ￥2341 | 有现货 |
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| 50MG | ￥3686 | 有现货 |
|
| 100MG | ￥5443 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PKR-IN-C16
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述PKR-IN-C16 is a specific protein kinase (PKR) inhibitor.?PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM.?
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产品描述PKR-IN-C16 is a specific protein kinase (PKR) inhibitor.?PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM.?PKR-IN-C16 protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress.?
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同义词——
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通路Others
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靶点Other Targets
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受体PKR
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研究领域——
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适应症——
化学信息
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CAS Number608512-97-6
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分子量268.29
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分子式C13H8N4OS
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纯度>98% (HPLC)
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溶解度DMSO:15.67 mg/mL(58.41 mM)
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SMILESO=C1Nc2ccc3ncsc3c2\C1=C\c1cnc[nH]1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Tronel C, et al. The specific PKR inhibitor C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component. Neurochem Int. 2014 Jan;64:73-83.
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