021-51111890
购物车（）
sales@molnova.cn
PFK-015
CAS No. 4382-63-2
PFK-015 ( PFK015; PFK 015; PFK015. )
产品货号. M18553 CAS No. 4382-63-2
PFK-015 is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥421 | 有现货 |
|
| 10MG | ￥656 | 有现货 |
|
| 25MG | ￥1312 | 有现货 |
|
| 50MG | ￥2406 | 有现货 |
|
| 100MG | ￥3572 | 有现货 |
|
| 200MG | ￥4957 | 有现货 |
|
| 500MG | ￥7906 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称PFK-015
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述PFK-015 is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).
-
产品描述PFK-015 is a potent inhibitor of PFKFB3. The preliminary results in a U87GM xenograft model have shown that PFK-015 has comparable activity to Temozolomide. PFK-015 inhibits glucoseuptake by tumors.
-
同义词PFK015; PFK 015; PFK015.
-
通路Others
-
靶点Other Targets
-
受体PFKFB3
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number4382-63-2
-
分子量260.29
-
分子式C17H12N2O
-
纯度98%
-
溶解度DMSO : 25.2 mg/mL 96.82 mM; H2O : < 0.1 mg/mL
-
SMILESC(=O)(/C=C/c1nc2c(cc1)cccc2)c1ccncc1
-
化学全称(E)-3-(pyridin-3-yl)-1-(quinolin-3-yl)prop-2-en-1-one
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Clem BF, et al. Mol Y Ther. 2013, 12(8), 1461-1470.
产品手册
关联产品
-
ErSO
ErSO is a selective activator of anticipatory unfolded protein response (UPR) via ERα receptor. ErSO can be used in studies about anti-cancer.
-
Cefazedone
Cefazedone is a semisynthetic first-generation cephalosporin?with activity against Gram-positive and Gram-negative bacteria.
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
