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PFK-015

CAS No. 4382-63-2

PFK-015 ( PFK015; PFK 015; PFK015. )

产品货号. M18553 CAS No. 4382-63-2

PFK-015 is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥421 有现货
10MG ¥656 有现货
25MG ¥1312 有现货
50MG ¥2406 有现货
100MG ¥3572 有现货
200MG ¥4957 有现货
500MG ¥7906 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    PFK-015
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    PFK-015 is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).
  • 产品描述
    PFK-015 is a potent inhibitor of PFKFB3. The preliminary results in a U87GM xenograft model have shown that PFK-015 has comparable activity to Temozolomide. PFK-015 inhibits glucoseuptake by tumors.
  • 同义词
    PFK015; PFK 015; PFK015.
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    PFKFB3
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    4382-63-2
  • 分子量
    260.29
  • 分子式
    C17H12N2O
  • 纯度
    98%
  • 溶解度
    DMSO : 25.2 mg/mL 96.82 mM; H2O : < 0.1 mg/mL
  • SMILES
    C(=O)(/C=C/c1nc2c(cc1)cccc2)c1ccncc1
  • 化学全称
    (E)-3-(pyridin-3-yl)-1-(quinolin-3-yl)prop-2-en-1-one

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Clem BF, et al. Mol Y Ther. 2013, 12(8), 1461-1470.
产品手册
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