PF9366 ( PF 9366;PF-9366 )

产品货号. M20081 CAS No. 72882-78-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

PF9366
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).
产品描述

PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).
同义词

PF 9366;PF-9366
通路

Others
靶点

Other Targets
受体

Mat2A
研究领域

——
适应症

——

CAS Number

72882-78-1
分子量

350.84
分子式

C20H19ClN4
纯度

>98% (HPLC)
溶解度

DMSO: 20 mg/mL (57 mM)
SMILES

CN(C)CCc1nnc2cc(-c3ccccc3)c3cc(Cl)ccc3n12
化学全称

2-(7-Chloro-5-phenyl-[124]triazolo[43-a]quinolin-1-yl)-NN-dimethylethan-1-amine

1.Quinlan CL et al. Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A. Nat Chem Biol. 2017 Jul;13(7):785-792.

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