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PF-592379
CAS No. 710655-15-5
PF-592379 ( PF592379;PF 592379 )
产品货号. M15724 CAS No. 710655-15-5
A potent, selective, orally active agonist of dopamine D3 receptor with EC50 of 21 nM; displays >470 and 180-fold functional selectivity over D2 and D4 dopamine receptors, respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7857 | 有现货 |
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| 50MG | ￥16038 | 有现货 |
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| 100MG | ￥20250 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PF-592379
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent, selective, orally active agonist of dopamine D3 receptor with EC50 of 21 nM; displays >470 and 180-fold functional selectivity over D2 and D4 dopamine receptors, respectively.
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产品描述A potent, selective, orally active agonist of dopamine D3 receptor with EC50 of 21 nM; displays >470 and 180-fold functional selectivity over D2 and D4 dopamine receptors, respectively; demonstrates activity in animal models of male erectile dysfunction.Sexual Dysfunction Preclinical
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同义词PF592379;PF 592379
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通路GPCR/G Protein
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靶点Dopamine Receptor
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受体Dopamine Receptor
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研究领域Endocrinology
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适应症Sexual Dysfunction
化学信息
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CAS Number710655-15-5
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分子量235.33
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分子式C13H21N3O
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纯度>98% (HPLC)
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溶解度——
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SMILESCCCN1CC(OCC1C)C2=CN=C(C=C2)N
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化学全称5-[(2R,5S)-5-methyl-4-propylmorpholin-2-yl]pyridin-2-amine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Attkins N, et al. Xenobiotica. 2010 Nov;40(11):730-42.
2. Collins GT, et al. Behav Pharmacol. 2012 Jun;23(3):280-91.
3. Thomsen M, et al. J Pharmacol Exp Ther. 2017 Jul;362(1):161-176.
2. Collins GT, et al. Behav Pharmacol. 2012 Jun;23(3):280-91.
3. Thomsen M, et al. J Pharmacol Exp Ther. 2017 Jul;362(1):161-176.
产品手册
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