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PF-06952229
CAS No. 1801333-55-0
PF-06952229 ( PF06952229 )
产品货号. M26371 CAS No. 1801333-55-0
PF-06952229 is an selective and orally active inhibitor of TGFbR1.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2341 | 有现货 |
|
| 10MG | ￥4026 | 有现货 |
|
| 25MG | ￥6423 | 有现货 |
|
| 50MG | ￥9153 | 有现货 |
|
| 100MG | ￥12312 | 有现货 |
|
| 500MG | ￥24057 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PF-06952229
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述PF-06952229 is an selective and orally active inhibitor of TGFbR1.
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产品描述PF-06952229 is an selective and orally active inhibitor of TGFbR1.(In Vivo):In MCF-7 ER+ HER2-xenograft breast cancer tumor model, PF-06952229 (30 mg/kg; gavage) combines with Palbociclib results in an improved inhibition of pSMAD2 and a significant increase in survival.
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同义词PF06952229
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通路Others
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靶点Other Targets
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受体MRP4; OAT1; OAT3
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研究领域——
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适应症——
化学信息
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CAS Number1801333-55-0
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分子量458.9
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分子式C23H24ClFN4O3
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纯度>98% (HPLC)
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溶解度——
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SMILESCC(C)c1cnc(cc1Nc1ccncc1C(=O)NC(CO)CO)-c1cc(Cl)ccc1F
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Kamiński T, Micha?owska M, Pawlak D. Aryl hydrocarbon receptor (AhR) and its endogenous agonist - indoxyl sulfate in chronic kidney disease. Postepy Hig Med Dosw (Online). 2017 Jul 30;71(0):624-632. Review.
产品手册
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