021-51111890
购物车（0）
sales@molnova.cn
PF-04745637
CAS No. 1917294-46-2
PF-04745637 ( —— )
产品货号. M26002 CAS No. 1917294-46-2
PF-04745637 是一种有效的选择性 TRPA1 拮抗剂，IC50 为 17 nM。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2001 | 有现货 |
|
| 10MG | ￥2795 | 有现货 |
|
| 25MG | ￥4722 | 有现货 |
|
| 50MG | ￥6747 | 有现货 |
|
| 100MG | ￥9315 | 有现货 |
|
| 500MG | ￥18549 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称PF-04745637
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述PF-04745637 是一种有效的选择性 TRPA1 拮抗剂，IC50 为 17 nM。
-
产品描述PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM.(In Vivo):PF-04745637 (topically applied; 50 mg/mL and 100 mg/mL) significantly reduces cinnamaldehyde-mediated flare in rat skin.
-
体外实验——
-
体内实验Topically applied PF-04745637 (Compound 8; 50 mg/mL and 100 mg/mL) significantly reduces cinnamaldehyde-mediated flare in rat skin.
-
同义词——
-
通路Membrane Transporter/Ion Channel
-
靶点TRP/TRPV Channel
-
受体Immunology/Inflammation related
-
研究领域——
-
适应症——
化学信息
-
CAS Number1917294-46-2
-
分子量509.01
-
分子式C27H32ClF3N2O2
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO : 125 mg/mL (245.58 mM)
-
SMILESOC1(CCN(CC1)C(CNC(=O)C1(CCCC1)c1ccc(Cl)cc1)Cc1ccccc1)C(F)(F)F
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Constituents of Compositae plants III. Anti-tumor promoting effects and cytotoxic activity against human cancer cell lines of triterpene diols and triols from edible chrysanthemum flowers.Cancer Lett., 2002, 177(1):7-12.
