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PF-01247324

CAS No. 875051-72-2

PF-01247324 ( PF-01247324; PF 01247324; PF01247324 )

产品货号. M19208 CAS No. 875051-72-2

PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥543 有现货
10MG ¥907 有现货
25MG ¥1968 有现货
50MG ¥3621 有现货
100MG ¥5451 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    PF-01247324
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).
  • 产品描述
    PF-01247324 is a novel selective and orally bioavailable Nav 1.8 channel blocker, attenuates nociception and sensory neuron excitability.
  • 同义词
    PF-01247324; PF 01247324; PF01247324
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Na(V1.8) channel
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    875051-72-2
  • 分子量
    330.6
  • 分子式
    C13H10Cl3N3O
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 30 mg/mL; 90.74 mM
  • SMILES
    CNC(=O)c1ccc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl
  • 化学全称
    6-amino-N-methyl-5-(2,3,5-trichlorophenyl)pyridine-2-carboxamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Payne CE, et al. A novel selective and orally bioavailable Nav 1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability. Br J Pharmacol. 2015 May;172(10):2654-70.
产品手册
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