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PF-00835231

CAS No. 870153-29-0

PF-00835231 ( —— )

产品货号. M28699 CAS No. 870153-29-0

PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-00835231 is the active compound of the first anti-3CLpro regimen in clinical trials.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1126 有现货
10MG ¥1847 有现货
25MG ¥3718 有现货
50MG ¥5565 有现货
100MG ¥7930 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    PF-00835231
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-00835231 is the active compound of the first anti-3CLpro regimen in clinical trials.
  • 产品描述
    PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-00835231 is the active compound of the first anti-3CLpro regimen in clinical trials.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    glucocerebrosidase
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    870153-29-0
  • 分子量
    944.1
  • 分子式
    C48H63N8O12
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC(C)C[C@@H](C(N[C@@H](C[C@H](CCN1)C1=O)C(CO)=O)=O)NC(c1cc(c(OC)ccc2)c2[nH]1)=OCC(C)C[C@@H](C(N[C@@H](C[C@H](CCN1)C1=O)C(CO)=O)=O)NC(c1cc(c(OC)ccc2)c2[nH]1)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Rogers S, et al. Discovery, SAR, and Biological Evaluation of Non-inhibitory Chaperones of Glucocerebrosidase. 2012 Mar 27 [updated 2013 Mar 7].
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