PDE9-IN-1
CAS No. 2305087-92-5
PDE9-IN-1 ( —— )
产品货号. M26362 CAS No. 2305087-92-5
PDE9-IN-1 is a potent, selective, and orally bioavailable Inhibitor of phosphodiesterase-9A (PDE9A)(IC50 of 8.7 nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1847 | 有现货 |
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10MG | ¥2876 | 有现货 |
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25MG | ¥4779 | 有现货 |
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50MG | ¥6958 | 有现货 |
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100MG | ¥9558 | 有现货 |
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500MG | ¥19197 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称PDE9-IN-1
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述PDE9-IN-1 is a potent, selective, and orally bioavailable Inhibitor of phosphodiesterase-9A (PDE9A)(IC50 of 8.7 nM).
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产品描述PDE9-IN-1 is a potent, selective, and orally bioavailable Inhibitor of phosphodiesterase-9A (PDE9A)(IC50 of 8.7 nM).(In Vivo):In the Unilateral common carotid artery occlusion (UCCAO) mouse model, PDE9-IN-1 (2.5-5.0 mg/kg; orally) significantly reduces the day 6 escape latency time, increases the frequency of platform area crossings, and recoveres learning and memory function. High dose group possibly improved the escape latency time of mice.
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同义词——
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通路Others
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靶点Other Targets
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受体NMDA receptor
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研究领域——
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适应症——
化学信息
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CAS Number2305087-92-5
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分子量362.4
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分子式C17H23FN6O2
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纯度>98% (HPLC)
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溶解度——
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SMILESC[C@@H](Nc1nc2n(ncc2c(=O)[nH]1)C1CCCC1)C(=O)N1CC[C@H](F)C1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Lozovaya N, Gataullina S, et al. Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model. Nat Commun. 2014 Aug 1;5:4563.
产品手册
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