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PD-L1-IN-3
CAS No. 2953044-29-4
PD-L1-IN-3 ( —— )
产品货号. M37233 CAS No. 2953044-29-4
PD-L1-IN-3 (Compound 4a) functions as an inhibitor of the PD-1/PD-L1 axis, with an IC50 value of 4.97 nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation. It antagonizes the PD-1/PD-L1 interaction by binding to the PD-L1 dimer, obstructing PD-1 signaling. This compound is utilized in research pertaining to lung cancer and melanoma [1].
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥1163 | 有现货 |
|
| 5MG | ￥1793 | 有现货 |
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| 10MG | ￥2867 | 有现货 |
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| 25MG | ￥5388 | 有现货 |
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| 50MG | ￥8524 | 有现货 |
|
| 100MG | ￥13235 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称PD-L1-IN-3
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述PD-L1-IN-3 (Compound 4a) functions as an inhibitor of the PD-1/PD-L1 axis, with an IC50 value of 4.97 nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation. It antagonizes the PD-1/PD-L1 interaction by binding to the PD-L1 dimer, obstructing PD-1 signaling. This compound is utilized in research pertaining to lung cancer and melanoma [1].
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产品描述PD-L1-IN-3 (Compound 4a) functions as an inhibitor of the PD-1/PD-L1 axis, with an IC50 value of 4.97 nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation. It antagonizes the PD-1/PD-L1 interaction by binding to the PD-L1 dimer, obstructing PD-1 signaling. This compound is utilized in research pertaining to lung cancer and melanoma .
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体外实验——
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体内实验——
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同义词——
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通路Immunology/Inflammation
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靶点PD-1/PD-L1
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受体PD-1/PD-L1
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研究领域——
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适应症——
化学信息
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CAS Number2953044-29-4
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分子量373.85
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分子式C19H15ClFN2OS
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纯度>98% (HPLC)
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溶解度——
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SMILES[Cl].N#CC1=C(OCC2=CC=C(C=C2)CN)SC=C1C=3C=CC(F)=CC3
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册
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