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首页- Products - GPCR/G Protein - Antibacterial - PA-824

PA-824

CAS No. 187235-37-6

PA-824 ( PA824;PA 824;Pretomanid;(S)-PA 824 )

产品货号. M12898 CAS No. 187235-37-6

A anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid; exhibits bactericidal activity against both replicating and static M. tuberculosis (MIC: 0.015-0.25 ug/mL).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ￥332 有现货
10MG ￥535 有现货
25MG ￥770 有现货
50MG ￥1004 有现货
100MG ￥1547 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
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生物学信息

  • 产品名称
    PA-824
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    A anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid; exhibits bactericidal activity against both replicating and static M. tuberculosis (MIC: 0.015-0.25 ug/mL).
  • 产品描述
    A anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid; exhibits bactericidal activity against both replicating and static M. tuberculosis (MIC: 0.015-0.25 ug/mL); shows potent bactericidal activity against MDR M. tuberculosis and promising oral activity in animal infection models.
  • 同义词
    PA824;PA 824;Pretomanid;(S)-PA 824
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    tuberculosis
  • 研究领域
    Infection
  • 适应症
    ——

化学信息

  • CAS Number
    187235-37-6
  • 分子量
    359.26
  • 分子式
    C14H12F3N3O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: ≥ 33 mg/mL
  • SMILES
    FC(F)(F)OC1=CC=C(C=C1)CO[C@H]2CN3C(OC2)=NC([N+]([O-])=O)=C3
  • 化学全称
    5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-, (6S)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Stover CK, et al. Nature. 2000 Jun 22;405(6789):962-6.
2. Tyagi S, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2289-93.
3. Lenaerts AJ, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2294-301.
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