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Olodaterol
CAS No. 868049-49-4
Olodaterol ( BI1744 CL )
产品货号. M16305 CAS No. 868049-49-4
A potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.COPDPhase 3 Clinical
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥1120 | 有现货 |
|
| 5MG | ￥2011 | 有现货 |
|
| 10MG | ￥3016 | 有现货 |
|
| 25MG | ￥6033 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Olodaterol
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.COPDPhase 3 Clinical
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产品描述A potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.COPD Phase 3 Clinical
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同义词BI1744 CL
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通路Angiogenesis
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靶点Adrenergic Receptor
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受体β2-adrenoceptor
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研究领域Inflammation/Immunology
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适应症COPD
化学信息
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CAS Number868049-49-4
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分子量386.44
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分子式C21H26N2O5
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纯度>98% (HPLC)
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溶解度H2O: 6.2 mg/mL
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SMILESCC(C)(CC1=CC=C(C=C1)OC)NCC(C2=C3C(=CC(=C2)O)NC(=O)CO3)O
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化学全称2H-1,4-Benzoxazin-3(4H)-one, 6-hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Bouyssou T, et al. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1410-4.
2. Bouyssou T,J Pharmacol Exp Ther. 2010 Jul;334(1):53-62. et al.
3. Wex E, et al. Br J Pharmacol. 2015 Jul;172(14):3537-47.
2. Bouyssou T,J Pharmacol Exp Ther. 2010 Jul;334(1):53-62. et al.
3. Wex E, et al. Br J Pharmacol. 2015 Jul;172(14):3537-47.
产品手册
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