OSMI-1 ( —— )

产品货号. M23755 CAS No. 1681056-61-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

OSMI-1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans.
产品描述

OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans. OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor (IC50: 2.7 μM).
同义词

——
通路

Others
靶点

Other Targets
受体

O-GlcNAc transferase (OGT)
研究领域

——
适应症

——

CAS Number

1681056-61-0
分子量

563.6
分子式

C28H25N3O6S2
纯度

>98% (HPLC)
溶解度

DMSO:83.33 mg/mL?(147.84 mM;?Need ultrasonic)
SMILES

O=C(N(CC1=CC=CS1)CC2=CC=CO2)[C@H](NS(C3=CC(C=C4)=C(C=C3)NC4=O)(=O)=O)C5=CC=CC=C5OC
化学全称

——

1.Ortiz-Meoz RF, et al. A small molecule that inhibits OGT activity in cells. ACS Chem Biol. 2015 Jun 19;10(6):1392-7.

计算器

产品手册

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