OSMI-1 ( —— )

产品货号. M23755 CAS No. 1681056-61-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

OSMI-1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans.
产品描述

OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans. OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor (IC50: 2.7 μM).
同义词

——
通路

Others
靶点

Other Targets
受体

O-GlcNAc transferase (OGT)
研究领域

——
适应症

——

CAS Number

1681056-61-0
分子量

563.6
分子式

C28H25N3O6S2
纯度

>98% (HPLC)
溶解度

DMSO:83.33 mg/mL?(147.84 mM;?Need ultrasonic)
SMILES

O=C(N(CC1=CC=CS1)CC2=CC=CO2)[C@H](NS(C3=CC(C=C4)=C(C=C3)NC4=O)(=O)=O)C5=CC=CC=C5OC
化学全称

——

1.Ortiz-Meoz RF, et al. A small molecule that inhibits OGT activity in cells. ACS Chem Biol. 2015 Jun 19;10(6):1392-7.

计算器

产品手册

关联产品

Gardoside methyl est...

The herbs of Duranta repens.
Gabapentin HCl

Gabapentin HCl is a GABA analogue, used to treat seizures and neuropathic pain.
Methyl nomilinate

Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.