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OSBPL7-IN-1
CAS No. 1269826-44-9
OSBPL7-IN-1 ( —— )
产品货号. M28764 CAS No. 1269826-44-9
OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2001 | 有现货 |
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| 10MG | ￥3216 | 有现货 |
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| 25MG | ￥5370 | 有现货 |
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| 50MG | ￥7655 | 有现货 |
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| 100MG | ￥10368 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称OSBPL7-IN-1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression.
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产品描述OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression.(In Vitro):OSBPL7-IN-1 (compound G; 1-10?μM) increase plasma membrane ATP-binding cassette transporter (ABCA1) in cultured human podocytes, and significantly increase ABCA1-dependent cholesterol efflux.(In Vivo):OSBPL7-IN-1 (100?mg/kg; oral gavage; daily; for 28 days) treatment normalizes proteinuria, and prevents renal function decline in mouse models of proteinuric kidney disease.
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number1269826-44-9
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分子量463.3
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分子式C20H19Cl2F3N2O3
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纯度>98% (HPLC)
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溶解度——
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SMILESO[C@H](CCCC1)[C@@H]1NC(c(cn1)cc(-c(cc2)cc(Cl)c2Cl)c1OCC(F)(F)F)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Atta-Ur-Rahman, Shabbir M, Khan AM, Hayat S, Nasreen A, Malik S, Choudhary MI. (1999) Chemical constituents from marine organisms. Natural Product Letters, 13, 255-261.
产品手册
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