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ONO-RS-082
CAS No. 99754-06-0
ONO-RS-082 ( —— )
产品货号. M27471 CAS No. 99754-06-0
ONO-RS-082 是一种不依赖 Ca2+ 的磷脂酶 A2 抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥356 | 有现货 |
|
| 5MG | ￥583 | 有现货 |
|
| 10MG | ￥988 | 有现货 |
|
| 25MG | ￥1912 | 有现货 |
|
| 50MG | ￥3467 | 有现货 |
|
| 100MG | ￥5176 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ONO-RS-082
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述ONO-RS-082 是一种不依赖 Ca2+ 的磷脂酶 A2 抑制剂。
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产品描述ONO-RS-082 is a Ca2+-independent phospholipase A2 inhibitor.?(In Vitro):ONO-RS-082 at 3.5 μM was able to inhibit epinephrine-stimulated thromboxane production in human platelets.?ONO-RS-082 could also disrupt endosome tubule formation and maintenance of the Golgi complex.
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体外实验Cell Viability Assay Cell Line:A549 lung epithelial cell lines Concentration:10 μM Incubation Time:2-h pretreatment Result:Completely blocked HXA3-mediated PAO1-induced PMN transepithelial migration. Largely prevented PAO1-induced PGE2 release.
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体内实验Animal Model:MCT- pulmonary hypertension (PH) rat model Dosage:50 mg/kg/day Administration:Result:Reduced the development of PH in the MCT-PH model for long-term.
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number99754-06-0
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分子量371.86
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分子式C21H22ClNO3
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (268.92 mM)
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SMILESCCCCCc1ccc(\C=C\C(=O)Nc2cc(Cl)ccc2C(O)=O)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Che L, et al. Feprazone Displays Antiadipogenesis and Antiobesity Capacities in in Vitro 3 T3-L1 Cells and in Vivo Mice. ACS Omega. 2021 Mar 7;6(10):6674-6680.
产品手册
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