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Nortadalafil

CAS No. 171596-36-4

Nortadalafil ( Demethyl Tadalafil )

产品货号. M20552 CAS No. 171596-36-4

Nortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥356 有现货
5MG ¥583 有现货
10MG ¥915 有现货
25MG ¥1725 有现货
50MG ¥3013 有现货
100MG ¥4836 有现货
200MG ¥6861 有现货
500MG ¥10206 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Nortadalafil
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Nortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
  • 产品描述
    Nortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
  • 同义词
    Demethyl Tadalafil
  • 通路
    Angiogenesis
  • 靶点
    PDE
  • 受体
    PDE5
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    171596-36-4
  • 分子量
    375.38
  • 分子式
    C21H16N3O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:50 mg/mL (133.20 mM)
  • SMILES
    O=C1CNC(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@H](N12)c1ccc2OCOc2c1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Takahiro R Nakamura S Kohno H et al. Contribution of CYP3A Isoforms to Dealkylation of PDE5 Inhibitors: A Comparison between Sildenafil N-Demethylation and Tadalafil Demethylenation[J]. Biological & Pharmaceutical Bulletin 2015 38(1):58-65.
产品手册
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