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Netupitant
CAS No. 290297-26-6
Netupitant ( AGE94200; AGE 94200;Ro 67-3189;Netupitant )
产品货号. M18372 CAS No. 290297-26-6
Netupitant is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥381 | 有现货 |
|
| 10MG | ￥551 | 有现货 |
|
| 25MG | ￥988 | 有现货 |
|
| 50MG | ￥1701 | 有现货 |
|
| 100MG | ￥3062 | 有现货 |
|
| 200MG | ￥4520 | 有现货 |
|
| 500MG | ￥7177 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Netupitant
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Netupitant is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).
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产品描述Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the activity of the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV).
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同义词AGE94200; AGE 94200;Ro 67-3189;Netupitant
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通路Others
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靶点Other Targets
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受体NK1
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number290297-26-6
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分子量578.59
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分子式C30H32F6N4O
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纯度98%
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溶解度DMSO : 23.2 mg/mL; 40.10 mM
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SMILESCc1ccccc1c1cc(ncc1N(C)C(=O)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)N1CCN(CC1)C
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化学全称2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)propanamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Rizzi A,etal.In vitro and in vivo pharmacological characterization of the novel NK receptor selective antagonist Netupitant.Peptides. 2012 Sep;37(1):86-97.
产品手册
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