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Nemorubicin

CAS No. 108852-90-0

Nemorubicin ( Methoxymorpholinyldoxorubicin ,PNU 152243 ,PNU-152243A )

产品货号. M22079 CAS No. 108852-90-0

Nemorubicin is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile.?

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥988 有现货
10MG ¥1596 有现货
25MG ¥3686 有现货
50MG ¥5443 有现货
100MG ¥7744 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Nemorubicin
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Nemorubicin is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile.?
  • 产品描述
    Nemorubicin is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile.?The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives.
  • 同义词
    Methoxymorpholinyldoxorubicin ,PNU 152243 ,PNU-152243A
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    108852-90-0
  • 分子量
    643.64
  • 分子式
    C32H37NO13
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:45 mg/mL (69.91 mM)
  • SMILES
    CO[C@@H]1CN(CCO1)[C@H]1C[C@H](O[C@H]2C[C@@](O)(Cc3c(O)c4C(=O)c5cccc(OC)c5C(=O)c4c(O)c23)C(=O)CO)O[C@@H](C)[C@H]1O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Quintieri L, et al. In vitro hepatic conversion of the anticancer agent nemorubicin to its active metabolite PNU-159682 in mice, rats and dogs: a comparison with human liver microsomes. Biochem Pharmacol. 2008 Sep 15;76(6):784-95.
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