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NVP-CGM097

CAS No. 1313363-54-0

NVP-CGM097 ( CGM097 )

产品货号. M23472 CAS No. 1313363-54-0

NVP-CGM097 is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥948 有现货
5MG ¥1758 有现货
10MG ¥2908 有现货
25MG ¥4803 有现货
50MG ¥6990 有现货
100MG ¥9639 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    NVP-CGM097
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    NVP-CGM097 is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).
  • 产品描述
    NVP-CGM097 is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).
  • 同义词
    CGM097
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    E1/E2/E3 Enzyme;MDM2
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1313363-54-0
  • 分子量
    659.3
  • 分子式
    C38H47ClN4O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:48 mg/mL (72.81 mM);Water:Insoluble
  • SMILES
    O=C1N(C2=CC=C(N(C)C[C@H]3CC[C@H](N4CC(N(C)CC4)=O)CC3)C=C2)[C@@H](C5=CC=C(Cl)C=C5)C6=C(C=C(OC)C(OC(C)C)=C6)C1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Holzer P, et al. Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors. J Med Chem. 2015 Aug 27;58(16):6348-58
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