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NSC632839
CAS No. 157654-67-6
NSC632839 ( NSC-632839;NSC 632839;Ubiquitin Isopeptidase-IN-F6 )
产品货号. M12253 CAS No. 157654-67-6
A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥381 | 有现货 |
|
| 10MG | ￥583 | 有现货 |
|
| 25MG | ￥1239 | 有现货 |
|
| 50MG | ￥2211 | 有现货 |
|
| 100MG | ￥3362 | 有现货 |
|
| 500MG | ￥7630 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称NSC632839
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.
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产品描述A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases; induce a unique apoptotic pathway, which includes a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa, stabilization of the IAP antagonist Smac, but also the involvement of the death receptor pathway.
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同义词NSC-632839;NSC 632839;Ubiquitin Isopeptidase-IN-F6
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通路Proteasome/Ubiquitin
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靶点DUB
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受体SENP2;USP2;USP7
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研究领域Cancer
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适应症——
化学信息
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CAS Number157654-67-6
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分子量339.86
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分子式C21H22ClNO
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纯度>98% (HPLC)
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溶解度DMSO: 6.2 mg/mL (Need warming)
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SMILESCC1=CC=C(C=C1)C=C2CNCC(=CC3=CC=C(C=C3)C)C2=O.Cl
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化学全称4-Piperidinone, 3,5-bis[(4-methylphenyl)methylene]-, hydrochloride (1:1)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Aleo E, et al. Cancer Res. 2006 Sep 15;66(18):9235-44.
2. Nicholson B, et al. Protein Sci. 2008 Jun;17(6):1035-43.
2. Nicholson B, et al. Protein Sci. 2008 Jun;17(6):1035-43.
产品手册
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