021-51111890
购物车（）
sales@molnova.cn
NSC632839
CAS No. 157654-67-6
NSC632839 ( NSC-632839;NSC 632839;Ubiquitin Isopeptidase-IN-F6 )
产品货号. M12253 CAS No. 157654-67-6
A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥381 | 有现货 |
|
| 10MG | ￥583 | 有现货 |
|
| 25MG | ￥1239 | 有现货 |
|
| 50MG | ￥2211 | 有现货 |
|
| 100MG | ￥3362 | 有现货 |
|
| 500MG | ￥7630 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称NSC632839
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.
-
产品描述A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases; induce a unique apoptotic pathway, which includes a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa, stabilization of the IAP antagonist Smac, but also the involvement of the death receptor pathway.
-
同义词NSC-632839;NSC 632839;Ubiquitin Isopeptidase-IN-F6
-
通路Proteasome/Ubiquitin
-
靶点DUB
-
受体SENP2;USP2;USP7
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number157654-67-6
-
分子量339.86
-
分子式C21H22ClNO
-
纯度>98% (HPLC)
-
溶解度DMSO: 6.2 mg/mL (Need warming)
-
SMILESCC1=CC=C(C=C1)C=C2CNCC(=CC3=CC=C(C=C3)C)C2=O.Cl
-
化学全称4-Piperidinone, 3,5-bis[(4-methylphenyl)methylene]-, hydrochloride (1:1)
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Aleo E, et al. Cancer Res. 2006 Sep 15;66(18):9235-44.
2. Nicholson B, et al. Protein Sci. 2008 Jun;17(6):1035-43.
2. Nicholson B, et al. Protein Sci. 2008 Jun;17(6):1035-43.
产品手册
关联产品
-
XL177A
XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34?nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.
-
VLX1570
VLX1570 is a small molecule b-AP15 analog that fucttion as proteasome deubiquitinase inhibitor with IC50 of 10 uM.
-
BRD 0476
BRD 0476 (ML187) is a selective, moderate inhibitor of ubiquitin-specific peptidase 9X (USP9X).
