NSC2805 ( 2-(2,5-dihydroxy-4-methylphenyl)-5-methylbenzene-1,4-diol )

产品货号. M28530 CAS No. 4371-34-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

NSC2805
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

NSC2805 是 WWP2（一种 E3 泛素连接酶）的抑制剂，IC50 为 0.38 μM。 NSC2805可用于抗癌研究。
产品描述

NSC2805 is an inhibitor of WWP2, an E3 ubiquitin ligase with an IC50 of 0.38 μM. NSC2805 can be used in anticancer studies.(In Vitro):NSC2805 significantly reduces the activity for WWP2, WWP1 and Nedd4 proteins and robustly inhibits WWP2-dependent PTEN ubiquitination.
体外实验

NSC2805 has WWP2 inhibitory activity with an IC50 of 0.38 μM.NSC2805 shows a significant reduction in activity for all three proteins (WWP2, WWP1 and Nedd4).NSC2805 can robustly inhibit WWP2-dependent PTEN ubiquitination.
体内实验

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同义词

2-(2,5-dihydroxy-4-methylphenyl)-5-methylbenzene-1,4-diol
通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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