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NRX-252262

CAS No. 2438637-61-5

NRX-252262 ( —— )

产品货号. M24123 CAS No. 2438637-61-5

NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50:3.8 nM)

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2325 有现货
10MG ¥3686 有现货
25MG ¥6099 有现货
50MG ¥8586 有现货
100MG ¥11583 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    NRX-252262
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50:3.8 nM)
  • 产品描述
    NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50:3.8 nM)
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    SCF(β-TrCP)-E3 ligase
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2438637-61-5
  • 分子量
    545.4
  • 分子式
    C23H17Cl2F3N2O4S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:8 mg/mL?(14.67 mM;?Need ultrasonic)
  • SMILES
    O=C1C(C(N2CC3=C(C=C(OC)C(OC)=C3)C2)=O)=C(SC4=C(Cl)C=CC=C4Cl)C=C(C(F)(F)F)N1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Kyle R. Simonetta, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications. 2019 March.
产品手册
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