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NLS-StAx-h

CAS No. ——

NLS-StAx-h ( —— )

产品货号. M30614 CAS No. ——

Wnt inhibitor (IC50 = 1.4 μM). Stapled peptide inhibitor of oncogenic Wnt signaling. Inhibits β-catenin-transcription factor interactions. Inhibits proliferation and migration of colorectal cancer cells. Cell permeable.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货

生物学信息

  • 产品名称
    NLS-StAx-h
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Wnt inhibitor (IC50 = 1.4 μM). Stapled peptide inhibitor of oncogenic Wnt signaling. Inhibits β-catenin-transcription factor interactions. Inhibits proliferation and migration of colorectal cancer cells. Cell permeable.
  • 产品描述
    Wnt inhibitor (IC50 = 1.4 μM). Stapled peptide inhibitor of oncogenic Wnt signaling. Inhibits β-catenin-transcription factor interactions. Inhibits proliferation and migration of colorectal cancer cells. Cell permeable.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    ——
  • 分子量
    3445.3
  • 分子式
    C161H275N55O29
  • 纯度
    >98% (HPLC)
  • 溶解度
    water:1 mg/mL
  • SMILES
    O=C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(NCCOCCOCC(N[C@@H](CCCCNC(N)=N)C(N[C@@H](CCCCNC(N)=N)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N3[C@@H](CCC3)C(N[C@@H](CCCCNC(N)=N)C(N[C@@](C)(CCC/C=C\CCC[C@@](C(N[C@H](CC4=CNC=N4)C(N[C@H](C(C)C)C(N[C@H](CCCCNC(N)=N)C(N[C@H](CCCCNC(N)=N)C(N[C@H](C(C)C)C(N[C@H](CC5=CNC6=CC=CC=C56)C(N[C@H](CCCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)(C)N7)C(N[C@@H]([C@@H](C)CC)C(N[C@H](CC(C)C)C(N[C@H](CC(O)=O)C7=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]8NCCC8
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Dietrich et al (2017) Cell permeable stapled peptide inhibitor of Wnt signaling that targets beta -catenin protein-protein Interactions. Cell Chem.Biol. 24 958 PMID:
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