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NITD-304

CAS No. 1473450-60-0

NITD-304 ( NITD304 )

产品货号. M12025 CAS No. 1473450-60-0

NITD-304 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 15 nM against M tuberculosis H37Rv.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥7857 有现货
50MG ¥16038 有现货
100MG ¥20250 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    NITD-304
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    NITD-304 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 15 nM against M tuberculosis H37Rv.
  • 产品描述
    NITD-304 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 15 nM against M tuberculosis H37Rv; shows potent activity against both drug-sensitive and multidrug-resistant clinical isolates of Mtb; demonstrates effectivity in treating both acute and chronic Mtb infections in mouse efficacy models.
  • 同义词
    NITD304
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibacterial
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1473450-60-0
  • 分子量
    339.27
  • 分子式
    C17H20Cl2N2O
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    O=C(C(N1)=CC2=C1C=C(Cl)C=C2Cl)NC3CCC(C)(C)CC3
  • 化学全称
    4,6-dichloro-N-(4,4-dimethylcyclohexyl)-1H-indole-2-carboxamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Rao SP, et al. Sci Transl Med. 2013 Dec 4;5(214):214ra168.
产品手册
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