N-Nornuciferine ( —— )

产品货号. M31415 CAS No. 4846-19-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

N-Nornuciferine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

N-Nornuciferine, an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).
产品描述

N-Nornuciferine, an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).
体外实验

The herb of lotus leaves is a commonly used traditional Chinese medicine with a wide range of pharmacological and physiological activities, particularly the reduction of the blood triglyceride and cholesterol levels. N-Nornuciferine strongly inhibits CYP2D6 activity but shows weak or no inhibition of the other four P450 isoenzymes (CYP2C19, CYP3A4, CYP2E1, CYP2C9). N-Nornuciferine competitively inhibits the CYP2D6-catalyzed dextromethorphan o-demethylation with apparent Ki values of 2.34 μM.
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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