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Milveterol

CAS No. 652990-07-3

Milveterol ( GSK 159797 )

产品货号. M15483 CAS No. 652990-07-3

Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥7857 有现货
50MG ¥16038 有现货
100MG ¥20250 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Milveterol
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays.
  • 产品描述
    Milveterol (GSK 159797) is a potent, selective long-acting β2 adrenoceptor agonist with pEC50 of 10.2 in cell-based assays, displays good β2/β1 selectivity (>300-fold); demonstrates high potency in vitro and long duration of action in a guinea pig model of bronchoprotection.Asthma Phase 2 Discontinued
  • 同义词
    GSK 159797
  • 通路
    Angiogenesis
  • 靶点
    Adrenergic Receptor
  • 受体
    Adrenergic Receptor
  • 研究领域
    Inflammation/Immunology
  • 适应症
    Asthma

化学信息

  • CAS Number
    652990-07-3
  • 分子量
    435.52
  • 分子式
    C25H29N3O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    C1=CC=C(C=C1)C(CNC2=CC=C(C=C2)CCNCC(C3=CC(=C(C=C3)O)NC=O)O)O
  • 化学全称
    N-(2-hydroxy-5-((R)-1-hydroxy-2-((4-(((R)-2-hydroxy-2-phenylethyl)amino)phenethyl)amino)ethyl)phenyl)formamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Jacobsen JR, et al. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1213-8.
2. Fuso L, et al. Curr Med Chem. 2013;20(12):1477-95.
3. Jacobsen JR, et al. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2625-30.
产品手册
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