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Methylproamine
CAS No. 188247-01-0
Methylproamine ( —— )
产品货号. M26297 CAS No. 188247-01-0
Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥551 | 有现货 |
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| 10MG | ￥786 | 有现货 |
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| 25MG | ￥1280 | 有现货 |
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| 50MG | ￥1936 | 有现货 |
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| 100MG | ￥2584 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Methylproamine
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.
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产品描述Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.(In Vitro):Immunocytochemical methods were used to measure the accumulation of phosphorylated H2AX (γH2AX) foci following ionizing radiation (IR) in patient-derived lymphoblastoid cells exposed to methylproamine. Pulsed field gel electrophoresis DNA damage and repair assays were performed to directly interrogate the action of methylproamine on DNA in irradiated cells.Methylproamine-treated cells had fewer γH2AX foci after IR compared to untreated cells. Also, the presence of methylproamine decreased the amount of lower molecular weight DNA entering the gel.
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同义词——
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通路Others
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靶点Other Targets
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受体α2 adrenergic receptor
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研究领域——
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适应症——
化学信息
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CAS Number188247-01-0
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分子量465.6
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分子式C28H31N7
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纯度>98% (HPLC)
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溶解度——
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SMILESCN(C)c1ccc(-c2nc3ccc(cc3[nH]2)-c2nc3ccc(cc3[nH]2)N2CCN(C)CC2)c(C)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Chopin, P., F.C. Colpaert, and M. Marien, Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway. J Pharmacol Exp Ther, 1999. 288(2): p. 798-804.
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