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Merck60
CAS No. 849234-64-6
Merck60 ( BRD 6929;Compound-60 )
产品货号. M16166 CAS No. 849234-64-6
Merck60 (BRD 6929, Compound-60)is a potent, selective and brain-penetrant inhibitor of HDAC1 and HDAC2 with IC50 of 1 nM and 8 nM respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥583 | 有现货 |
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| 10MG | ￥1126 | 有现货 |
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| 25MG | ￥2406 | 有现货 |
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| 50MG | ￥4350 | 有现货 |
|
| 100MG | ￥6278 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Merck60
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Merck60 (BRD 6929, Compound-60)is a potent, selective and brain-penetrant inhibitor of HDAC1 and HDAC2 with IC50 of 1 nM and 8 nM respectively.
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产品描述Merck60 (BRD 6929, Compound-60)is a potent, selective and brain-penetrant inhibitor of HDAC1 and HDAC2 with IC50 of 1 nM and 8 nM respectively; displays 50-400 fold selectivity over class I HDAC3 (IC50=458 nM) and no appreciable inhibition of HDAC8 or of the class II HDACs (IC50>30 uM); alters gene expression in brain circuits involved in mood regulation, improves mood-related behaviors in mice.
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同义词BRD 6929;Compound-60
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通路Cell Cycle/DNA Damage
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靶点HDAC
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受体HDAC
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研究领域——
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适应症——
化学信息
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CAS Number849234-64-6
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分子量351.42
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分子式C19H17N3O2S
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称4-acetamido-N-(2-amino-5-(thiophen-2-yl)phenyl)benzamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Schroeder FA, et al. PLoS One. 2013 Aug 14;8(8):e71323.
2. Methot JL, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):973-8.
3. Stubbs MC, et al. Clin Cancer Res. 2015 May 15;21(10):2348-58.
2. Methot JL, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):973-8.
3. Stubbs MC, et al. Clin Cancer Res. 2015 May 15;21(10):2348-58.
产品手册
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