Mecillinam
CAS No. 32887-01-7
Mecillinam ( Amdinocillin | AMDINOCILLIN | Coactin | Penicillin HX | Mecillinamum | Hexacillin )
产品货号. M24265 CAS No. 32887-01-7
美西林是一种广谱青霉素抗生素,通过与青霉素结合蛋白 2 (PBP2) 特异性结合,被认为对革兰氏阴性菌具有活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
10MG | ¥316 | 有现货 |
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25MG | ¥478 | 有现货 |
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100MG | ¥915 | 有现货 |
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200MG | ¥1361 | 有现货 |
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500MG | ¥2292 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Mecillinam
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述美西林是一种广谱青霉素抗生素,通过与青霉素结合蛋白 2 (PBP2) 特异性结合,被认为对革兰氏阴性菌具有活性。
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产品描述Mecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2). It is used primarily to treat urinary tract infections and has also been used in the treatment of paratyphoid fever and typhoid.
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体外实验——
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体内实验Animal Model:Mecillinam (Amdinocillin, 400 mg per kg) is effective for the treatment of catheterassociated infections at high dosages (400 mg per kg of body weight/d).Dosage:50, 100, 200, and 400 mg per kg. Administration:Intravenously each day in four divided doses over a 72-h period.Result:High dose of 400 mg/kg exhibited significant activity.
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同义词Amdinocillin | AMDINOCILLIN | Coactin | Penicillin HX | Mecillinamum | Hexacillin
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通路GPCR/G Protein
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靶点Antibacterial
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受体Bacterial
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研究领域——
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适应症——
化学信息
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CAS Number32887-01-7
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分子量325.43
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分子式C15H23N3O3S
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纯度>98% (HPLC)
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溶解度DMSO:Soluble; Water:Insoluble
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SMILESCC1([C@@H](N2[C@H](S1)[C@@H](C2=O)N=CN3CCCCCC3)C(=O)O)C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Thulin E, Sundqvist M, Andersson DI. Amdinocillin (Mecillinam) resistance mutations in clinical isolates and laboratory-selected mutants of Escherichia coli. Antimicrob Agents Chemother. 2015 Mar;59(3):1718-27.