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Mcl1-IN-2
CAS No. 292057-76-2
Mcl1-IN-2 ( Mcl1-IN-2 | Mcl1IN2 | Mcl1 IN 2 | Mcl1-inhibitor-2 | Mcl1 inhibitor 2 )
产品货号. M13898 CAS No. 292057-76-2
Mcl1-IN-2 是一种 Mcl-1 抑制剂，未报告 IC50 值。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥956 | 有现货 |
|
| 5MG | ￥1604 | 有现货 |
|
| 10MG | ￥2657 | 有现货 |
|
| 25MG | ￥4479 | 有现货 |
|
| 50MG | ￥6448 | 有现货 |
|
| 100MG | ￥8829 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Mcl1-IN-2
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Mcl1-IN-2 是一种 Mcl-1 抑制剂，未报告 IC50 值。
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产品描述Mcl1-IN-2 is an Mcl-1 inhibitor without a reported IC50 value.
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体外实验IMB-XH1 (Compound 2) is a Mcl-1 inhibitor. IMB-XH is screened out with the IC50 value of 0.4637 μM at the concentration of 20 μg/mL. IMB-XH1 (20 μg/mL) can increase the sensitivity of E. coli BL21 (DE3) (pET-30a(+)-NDM-1) to ampicillinby more than 8 times. IMB-XHI may have a broad spectrum of metallo-β-lactamases (MBLs) inhibitory activity. The combination of IMB-XH1 and Meropenem (MEM) may have potentials to treat infections caused by metallo-β-lactamases-positive, carbapenem-resistant Gram-negative pathogens.
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体内实验——
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同义词Mcl1-IN-2 | Mcl1IN2 | Mcl1 IN 2 | Mcl1-inhibitor-2 | Mcl1 inhibitor 2
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通路Angiogenesis
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靶点Bcl-2
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受体Bcl-2
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研究领域Cancer
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适应症——
化学信息
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CAS Number292057-76-2
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分子量333.4069
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分子式C19H15N3OS
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESOC(C(N=CC=C1)=C1C=C2)=C2C(C3=CC=CS3)NC4=CC=CC=N4
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化学全称8-Quinolinol, 7-[(2-pyridinylamino)-2-thienylmethyl]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Richard DJ, et al. Bioorg Med Chem. 2013 Nov 1;21(21):6642-9.
2. Zaneta Nikolovska-Coleska, et al. Discovery and characterization of new small-molecule inhibitors of Mcl-1 by high-throughput screening. AACR 2008.
