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McN3716
CAS No. 69207-52-9
McN3716 ( Methyl palmoxirate; NSC359682 )
产品货号. M21897 CAS No. 69207-52-9
McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7857 | 有现货 |
|
| 50MG | ￥16038 | 有现货 |
|
| 100MG | ￥20250 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称McN3716
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor.
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产品描述Inhibition of brain mitochondrial β-oxidation by McN3716 (Methyl palmoxirate, MEP) significantly reduces the levels of all measured HETE and epoxytrienoic acids (EET), nonenzymatic auto-oxidative metabolites of ARA, by 23% to 44% and 32% to 50% compared with vehicle-injected rats, respectively, except for 15-HETE which was unaffected. There is a significant 34% reduction in the level of 6-keto-PGF1α, a byproduct of PGI2 (prostacyclin) in McN3716-treated rats. Similarly, the brain level of hydroxyeicosapentaenoic acids, nonenzymatic auto-oxidative metabolites of EPA, is reduced by 35% to 76% upon McN3716 treatment relative to vehicle.
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同义词Methyl palmoxirate; NSC359682
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通路Others
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靶点Other Targets
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受体Carnitine palmitoyltransferase I (CPT-1)
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研究领域——
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适应症——
化学信息
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CAS Number69207-52-9
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分子量298.46
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分子式C18H34O3
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(C1(CCCCCCCCCCCCCC)OC1)OC
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Chen CT, et al. Inhibiting mitochondrial β-oxidation selectively reduces levels of nonenzymatic oxidative polyunsaturated fatty acid metabolites in the brain. J Cereb Blood Flow Metab. 2014 Mar;34(3):376-9.
产品手册
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