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首页- Products - Others - Other Targets - McN3716

McN3716

CAS No. 69207-52-9

McN3716 ( Methyl palmoxirate; NSC359682 )

产品货号. M21897 CAS No. 69207-52-9

McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ￥7857 有现货
50MG ￥16038 有现货
100MG ￥20250 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
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生物学信息

  • 产品名称
    McN3716
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor.
  • 产品描述
    Inhibition of brain mitochondrial β-oxidation by McN3716 (Methyl palmoxirate, MEP) significantly reduces the levels of all measured HETE and epoxytrienoic acids (EET), nonenzymatic auto-oxidative metabolites of ARA, by 23% to 44% and 32% to 50% compared with vehicle-injected rats, respectively, except for 15-HETE which was unaffected. There is a significant 34% reduction in the level of 6-keto-PGF1α, a byproduct of PGI2 (prostacyclin) in McN3716-treated rats. Similarly, the brain level of hydroxyeicosapentaenoic acids, nonenzymatic auto-oxidative metabolites of EPA, is reduced by 35% to 76% upon McN3716 treatment relative to vehicle.
  • 同义词
    Methyl palmoxirate; NSC359682
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Carnitine palmitoyltransferase I (CPT-1)
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    69207-52-9
  • 分子量
    298.46
  • 分子式
    C18H34O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    O=C(C1(CCCCCCCCCCCCCC)OC1)OC
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Chen CT, et al. Inhibiting mitochondrial β-oxidation selectively reduces levels of nonenzymatic oxidative polyunsaturated fatty acid metabolites in the brain. J Cereb Blood Flow Metab. 2014 Mar;34(3):376-9.
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