Mc-Val-Cit-PAB-Cl
CAS No. 1639351-92-0
Mc-Val-Cit-PAB-Cl ( —— )
产品货号. M26985 CAS No. 1639351-92-0
Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥3038 | 有现货 |
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10MG | ¥4520 | 有现货 |
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25MG | ¥7274 | 有现货 |
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50MG | ¥9963 | 有现货 |
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100MG | ¥13446 | 有现货 |
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500MG | ¥26892 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Mc-Val-Cit-PAB-Cl
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE.
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产品描述Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). Mc-Val-Cit-PAB-Cl is a cleavable ADC linker.
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number1639351-92-0
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分子量591.1
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分子式C28H39ClN6O6
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纯度>98% (HPLC)
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溶解度——
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SMILESCC(C)[C@H](NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CCl)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Remirez D, et al. Mechanism of protection of lobenzarit against paracetamol-induced toxicity in rat hepatocytes. Eur J Pharmacol. 1995 Dec 7;293(4):301-8.
产品手册
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