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MLS0315771
CAS No. 727664-91-7
MLS0315771 ( —— )
产品货号. M22503 CAS No. 727664-91-7
MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM).MLS0315771 is toxic to the zebrafish embryos above 2 μM. MLS0315771 toxicity at higher concentrations is an off-target effect.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥915 | 有现货 |
|
| 10MG | ￥1393 | 有现货 |
|
| 25MG | ￥2608 | 有现货 |
|
| 50MG | ￥3467 | 有现货 |
|
| 100MG | ￥4633 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称MLS0315771
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM).MLS0315771 is toxic to the zebrafish embryos above 2 μM. MLS0315771 toxicity at higher concentrations is an off-target effect.
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产品描述MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM).MLS0315771 is toxic to the zebrafish embryos above 2 μM. MLS0315771 toxicity at higher concentrations is an off-target effect. MLS0315771 enhances mannose flux toward glycosylation. It ~50% of embryos appeared sick within 20 min at 8-10 μM, and most of them die by 30-60 min.
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同义词——
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通路Others
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靶点Other Targets
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受体MPI
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研究领域——
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适应症——
化学信息
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CAS Number727664-91-7
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分子量273.33
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分子式C15H12FNOS
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纯度>98% (HPLC)
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溶解度——
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SMILESCc1ccc(C)c(c1)-n1sc2cc(F)ccc2c1=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Sharma V, et al. Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts. J Biol Chem. 2011 Nov 11;286(45):39431-8.
产品手册
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