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ML390
CAS No. 2029049-79-2
ML390 ( —— )
产品货号. M22425 CAS No. 2029049-79-2
ML390对多种白血病模型发挥有效的分化作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥446 | 有现货 |
|
| 10MG | ￥583 | 有现货 |
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| 25MG | ￥988 | 有现货 |
|
| 50MG | ￥1531 | 有现货 |
|
| 100MG | ￥2722 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ML390
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述ML390对多种白血病模型发挥有效的分化作用。
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产品描述ML390 exerts its potent differentiation effect on multiple leukemia models.
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体外实验ML390 is active with an ED50 of ~2 μM in murine and human AML cell lines. In vitro, treatment of Lys-GFP-ER-HoxA9 cells with ML390 for 48 hr inhibits DHODH activity, leading to the dramatic (>500-fold) accumulation of the upstream metabolite DHO and the depletion of uridine and other downstream metabolites.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number2029049-79-2
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分子量406.4
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分子式C21H21F3N2O3
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纯度>98% (HPLC)
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溶解度DMSO:27 mg/mL (66.44 mM)
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SMILESFC(F)(F)Oc1ccc(cc1)C(=O)NCCC(=O)N[C@@H]1CCCc2ccccc12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Sykes DB et al. Discovering Small Molecules that Overcome Differentiation Arrest in Acute Myeloid Leukemia. National Center for Biotechnology Information (US); 2010-2013 Dec 15.
产品手册
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