ML277
CAS No. 1401242-74-7
ML277 ( CID-53347902 )
产品货号. M23558 CAS No. 1401242-74-7
ML277 was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥575 | 有现货 |
|
10MG | ¥1069 | 有现货 |
|
25MG | ¥1985 | 有现货 |
|
50MG | ¥3669 | 有现货 |
|
100MG | ¥5403 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称ML277
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述ML277 was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).
-
产品描述ML277 was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).
-
同义词CID-53347902
-
通路Cell Cycle/DNA Damage
-
靶点Potassium Channel
-
受体KCNQ1
-
研究领域——
-
适应症——
化学信息
-
CAS Number1401242-74-7
-
分子量471.6
-
分子式C23H25N3O4S2
-
纯度>98% (HPLC)
-
溶解度DMSO:≥60 mg/mL (127.23mM)
-
SMILESO=C([C@@H]1N(S(=O)(C2=CC=C(C)C=C2)=O)CCCC1)NC3=NC(C4=CC=C(OC)C=C4)=CS3
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Mattmann ME, Yu H, Lin Z, et al. Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. Bioorg Med Chem Lett. 2012;22(18):5936-5941. doi:10.1016/j.bmcl.2012.07.060
产品手册
关联产品
-
BMS-813160
BMS-813160 is the first dualCCR2/CCR5antagonist to enter Clinical development for cardiovascular.
-
Hydroquinidine
Dihydroquinidine is an organic compound and as a cinchona alkaloid closely related to quinine.
-
BeKm 1
Potent and selective KV11.1 (hERG) channel blocker. Selective for KV11.1 over a panel of 14 other potassium channels. Dose-dependently prolongs QTc interval in isolated rabbit heart.