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ML277

CAS No. 1401242-74-7

ML277 ( CID-53347902 )

产品货号. M23558 CAS No. 1401242-74-7

ML277 was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥575 有现货
10MG ¥1069 有现货
25MG ¥1985 有现货
50MG ¥3669 有现货
100MG ¥5403 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    ML277
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    ML277 was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).
  • 产品描述
    ML277 was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM).
  • 同义词
    CID-53347902
  • 通路
    Cell Cycle/DNA Damage
  • 靶点
    Potassium Channel
  • 受体
    KCNQ1
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1401242-74-7
  • 分子量
    471.6
  • 分子式
    C23H25N3O4S2
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:≥60 mg/mL (127.23mM)
  • SMILES
    O=C([C@@H]1N(S(=O)(C2=CC=C(C)C=C2)=O)CCCC1)NC3=NC(C4=CC=C(OC)C=C4)=CS3
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Mattmann ME, Yu H, Lin Z, et al. Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. Bioorg Med Chem Lett. 2012;22(18):5936-5941. doi:10.1016/j.bmcl.2012.07.060
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