ML265
CAS No. 1221186-53-3
ML265 ( TEPP-46 )
产品货号. M20635 CAS No. 1221186-53-3
ML265 is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1 PKL and PKRinduces tetramerization and reduces tumor formation and size in a mouse xenograft model.?.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥786 | 有现货 |
|
10MG | ¥1191 | 有现货 |
|
50MG | ¥3021 | 有现货 |
|
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称ML265
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述ML265 is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1 PKL and PKRinduces tetramerization and reduces tumor formation and size in a mouse xenograft model.?.
-
产品描述ML265 is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1 PKL and PKRinduces tetramerization and reduces tumor formation and size in a mouse xenograft model.?
-
同义词TEPP-46
-
通路Others
-
靶点Other Targets
-
受体PKM2
-
研究领域——
-
适应症——
化学信息
-
CAS Number1221186-53-3
-
分子量372.46
-
分子式C17H16N4O2S2
-
纯度>98% (HPLC)
-
溶解度DMSO:50 mg/mL (134.24 mM)
-
SMILESCn1c2cc(sc2c2cnn(Cc3cccc(N)c3)c(=O)c12)S(C)=O
-
化学全称6-(3-aminobenzyl)-4-methyl-2-(methylsulfinyl)-46-dihydro-5H-thieno[2'3':45]pyrrolo[23-d]pyridazin-5-one
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Walsh M J Brimacombe K R Anastasiou D et al. ML265: A potent PKM2 activator induces tetramerization and reduces tumor formation and size in a mouse xenograft model[M]// Probe Reports from the NIH Molecular Libraries Program. PubMed 2009.
产品手册
关联产品
-
ELOVL6-IN-1
ELOVL6-IN-1 is a potent, orally active and selective?ELOVL6?inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse?ELOVL6?activities.
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.