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ML221
CAS No. 877636-42-5
ML221 ( ML221; ML 221; ML-221 )
产品货号. M17640 CAS No. 877636-42-5
ML221 is a potentapelin /APJfunctional antagonist, inhibiting apelin-13-mediated activation of APJ, withIC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, andEC80of 10 nM in both assays.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥405 | 有现货 |
|
| 10MG | ￥632 | 有现货 |
|
| 25MG | ￥1369 | 有现货 |
|
| 50MG | ￥2082 | 有现货 |
|
| 100MG | ￥3791 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ML221
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述ML221 is a potentapelin /APJfunctional antagonist, inhibiting apelin-13-mediated activation of APJ, withIC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, andEC80of 10 nM in both assays.
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产品描述ML221 is a potentapelin /APJfunctional antagonist, inhibiting apelin-13-mediated activation of APJ, withIC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, andEC80of 10 nM in both assays.
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同义词ML221; ML 221; ML-221
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通路Others
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靶点Other Targets
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受体APJ
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number877636-42-5
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分子量385.35
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分子式C17H11N3O6S
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纯度98%
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溶解度DMSO : ≥ 31 mg/mL; 80.45 mM
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SMILESC1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)[N+](=O)[O-]
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化学全称[4-oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-nitrobenzoate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Maloney PR, etal.Bioorg Med Chem Lett. 2012 Nov 1;22(21):6656-60.
产品手册
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