ML188
CAS No. 1417700-13-0
ML188 ( —— )
产品货号. M21931 CAS No. 1417700-13-0
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥875 | 有现货 |
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5MG | ¥1442 | 有现货 |
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10MG | ¥2341 | 有现货 |
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25MG | ¥4795 | 有现货 |
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50MG | ¥7736 | 有现货 |
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100MG | ¥10368 | 有现货 |
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200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
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生物学信息
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产品名称ML188
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
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产品描述ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.Probe 16-(R) (ML188) is a modest molecular weight SARS-CoV 3CLpro inhibitor with demonstrated antiviral activity and a non-covalent mechanism of action.
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同义词——
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通路Others
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靶点Other Targets
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受体SARS-CoV
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研究领域——
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适应症——
化学信息
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CAS Number1417700-13-0
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分子量433.54
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分子式C26H31N3O3
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纯度>98% (HPLC)
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溶解度——
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SMILESCC(C)(C)NC(=O)[C@H](N(C(=O)c1ccco1)c1ccc(cc1)C(C)(C)C)c1cccnc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Jacobs J , Grum-Tokars V , Zhou Y , et al. Discovery, Synthesis, And Structure-Based Optimization of a Series of?N?-(?tert?-Butyl)-2-(?N?-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease[J]. Journal of Medicinal Chemistry, 2013, 56(2):534-546.
产品手册
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