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ML188

CAS No. 1417700-13-0

ML188 ( —— )

产品货号. M21931 CAS No. 1417700-13-0

ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥875 有现货
5MG ¥1442 有现货
10MG ¥2341 有现货
25MG ¥4795 有现货
50MG ¥7736 有现货
100MG ¥10368 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    ML188
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
  • 产品描述
    ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.Probe 16-(R) (ML188) is a modest molecular weight SARS-CoV 3CLpro inhibitor with demonstrated antiviral activity and a non-covalent mechanism of action.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    SARS-CoV
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1417700-13-0
  • 分子量
    433.54
  • 分子式
    C26H31N3O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC(C)(C)NC(=O)[C@H](N(C(=O)c1ccco1)c1ccc(cc1)C(C)(C)C)c1cccnc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Jacobs J , Grum-Tokars V , Zhou Y , et al. Discovery, Synthesis, And Structure-Based Optimization of a Series of?N?-(?tert?-Butyl)-2-(?N?-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease[J]. Journal of Medicinal Chemistry, 2013, 56(2):534-546.
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