021-51111890
购物车（0）
sales@molnova.cn
MKK7-COV-9
CAS No. ——
MKK7-COV-9 ( MKK7 Covalen inhibitor 9 )
产品货号. M16996 CAS No. ——
MKK7-COV-9（MKK7 Covalen 抑制剂 9）是一种有效的、选择性的共价 MKK7 抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称MKK7-COV-9
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述MKK7-COV-9（MKK7 Covalen 抑制剂 9）是一种有效的、选择性的共价 MKK7 抑制剂。
-
产品描述MKK7-COV-9 (MKK7 Covalen inhibitor 9) is a potent, selective, covalent MKK7 inhibitor, displays >1,000-fold selectivity over MKK4; displays remarkable selectivity against a kinome panel of 76 kinases; inhibits the CD86+ response in primary mouse B cells in response to LPS stimulation (EC50=4.9 uM); has half-lives >40 min in dog and rat, and significantly improved stability in human and monkey liver microsomes; MKK7-COV-9 is not cytotoxic to a panel of human cell lines.
-
体外实验——
-
体内实验——
-
同义词MKK7 Covalen inhibitor 9
-
通路MAPK/ERK Signaling
-
靶点MEK
-
受体MEK
-
研究领域——
-
适应症——
化学信息
-
CAS Number——
-
分子量320.352
-
分子式C18H16N4O2
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称3-acrylamido-5-(1H-indazol-3-yl)-N-methylbenzamide
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Shraga A, et al. Cell Chem Biol. 2018 Oct 24. pii: S2451-9456(18)30344-1.
