MKC9989 ( —— )

产品货号. M26299 CAS No. 1338934-20-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

MKC9989
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

MKC9989 is an inhibitor of Hydroxy aryl aldehydes (HAA). MKC9989 also inhibits IRE1α with an IC50 of 0.23 to 44 μM.
产品描述

MKC9989 is an inhibitor of Hydroxy aryl aldehydes (HAA). MKC9989 also inhibits IRE1α with an IC50 of 0.23 to 44 μM.(In Vitro):MKC9989, significantly stabilizes the RIDD target CD59 mRNA when co-administered with thapsigargin relative to thapsigargin treatment alone and modestly increases levels of CD59 mRNA in non-stressed cells, the latter likely reflects the inhibition of baseline RIDD activity. In contrast to effects on XBP1 splicing, MKC9989 moderately stabilizes CD59 levels when administered 2 hour post treatment with thapsigargin..
同义词

——
通路

Others
靶点

Other Targets
受体

——
研究领域

——
适应症

——

1.Brent R. StockwellWan Seok YangRohitha SriRamaratnam. Oncogenic-RAS-signal dependent lethal compounds.US8546421B1

计算器

产品手册

关联产品

Octahydroaminoacridi...

Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.
Methyl nomilinate

Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
Deruxtecan

Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.